AMR Salmonella

  • Recently, a new study said that a new target was found to combat AMR Salmonella.
  • The study showed that outer membrane porins of Salmonella typhimurium play an essential role in the survival of the bacteria in the presence of antibiotics.
  • Deleting outer membrane protein A (OmpA) from Salmonella hampered its survival in the presence of two β-lactam drugs — ceftazidime and meropenem.
  • OmpA is one of the most abundant barrel-shaped porin proteins localised in the outer membrane of Salmonella.
  • The absence of OmpA in Salmonella hampers the stability of the bacterial outer membrane and reduces the expression of ....
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