Directed Protein Evolution

A team of scientists recently developed a new method of directed protein evolution to optimize proteins directly in mammalian cells for various applications. This has taken protein engineering efforts to a new level.

Directed Protein Evolution

  • In the current research, using a new method of directed evolution of proteins, scientists successfully created a fluorescent protein named mCRISPRred, which fluoresces brightly in lysosomes- the highly acidic cell vesicles that are difficult to label.
  • In directed evolution of proteins, large numbers of slightly altered variants of a starting protein are produced, thus creating a large pool of potential candidates for later use in ....
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