Innovative SMaRT-PCR Mask Revolutionizes Child TB Diagnosis

A groundbreaking study funded by ICMR introduces SMaRT-PCR mask for non-invasive tuberculosis diagnosis in children, offering hope for accurate and trauma-free detection.

Key Points

What is the SMaRT-PCR Mask: The modified N95 mask collects exhaled respiratory aerosols for TB detection via RT-PCR, providing a one-time-use solution.
High TB Burden in Indian Children: India faces 30% of global paediatric TB cases, but diagnosing TB in children is challenging due to non-specific symptoms.
Challenges in TB Diagnosis for Children: Invasive procedures like gastric lavage are traumatic, leading to hesitancy for diagnosis among parents.
Non-Invasive SMaRT-PCR Method: The SMaRT-PCR procedure is non-invasive, requiring only a 10-minute mask-wearing session for sample collection.
Promising Results: Initial studies show SMaRT-PCR method has a sensitivity of 75%, outperforming standard diagnosis methods.
Future Prospects: The SMaRT-PCR mask offers hope for accurate and trauma-free TB diagnosis in children, potentially transforming paediatric healthcare.