Google's DeepMind AI Predicts Disease-Causing Genetic Mutations
Recently, scientists harnessed Google's DeepMind AI tool to create a program capable of predicting whether genetic mutations lead to diseases or remain harmless, offering a breakthrough in human genetics.
- DeepMind has introduced a catalogue of 'missense' mutations, which are genetic alterations affecting the function of human proteins, through their AI model AlphaMissense.
- Missense variants are single-letter DNA substitutions that can lead to different amino acids within a protein, potentially causing diseases such as cystic fibrosis, sickle-cell anemia, or cancer.
- AlphaMissense utilizes the AlphaFold model to distinguish between variants observed in human and related primate populations, categorizing commonly seen variants ....
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