Study Reveals How Cell Microenvironment Stiffness Affects Tissue Form

Recently, an interdisciplinary research team from the Indian Institute of Science (IISc) has revealed the impact of a cell's microenvironment stiffness on its structure and function, offering insights into tissue healing and scar formation.

  • Inefficient wound healing can lead to tissue fibrosis and scar formation, with implications for conditions like cardiac arrest and diseases such as cancer.
  • Changes in stiffness influenced cell structure and function, with fibroblasts on less stiff substrates showing rounder shapes, altered cytoskeleton protein levels, cell cycle arrest, reduced growth rates, and cell death.
  • The research focused on Transforming Growth Factor-β (TGF-β) as the master regulator ....
Do You Want to Read More?
Subscribe Now

To get access to detailed content

Already a Member? Login here


Take Annual Subscription and get the following Advantage
The annual members of the Civil Services Chronicle can read the monthly content of the magazine as well as the Chronicle magazine archives.
Readers can study all the material before the last six months of the Civil Services Chronicle monthly issue in the form of Chronicle magazine archives.

Related Content