PIB Corner

Zebrafish & Heart Regeneration

  • Scientists at Pune-based Agharkar Research Institute have used Zebrafish model and identified genes that can promote heart regeneration.
  • Scientists have identified the cellular communication network factor 2a (ccn2a), a gene that can promote heart regeneration by enhancing cardiomyocyte proliferation.
  • Ccn2a promotes the innate regenerative response of the adult zebrafish heart and maybe a promising therapeutic target for humans.
  • Zebrafish – a tiny freshwater fish barely 2-3 cm long can efficiently regenerate its damaged heart within a short time period. Found in South Asia, it is a popular aquarium fish, frequently sold under the trade name Danio.
  • A ....
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